Fertility-sparing surgery, with subsequent pregnancy, in persistent gestational trophoblastic neoplasia: Case report

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Fertility-sparing surgery, with subsequent pregnancy, in persistent gestational trophoblastic neoplasia: case report.

Gestational trophoblastic neoplasia (GTN) is primarily a disease of women of reproductive age. In most instances, it is cured by surgical evacuation of the uterus, with persistent disease being very sensitive to chemotherapy. Hysterectomy, recommended for persistent chemotherapy-resistant uterine disease, may be unacceptable to the woman who wishes to maintain her fertility. Uterine resection o...

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Fertility sparing surgery in gestational trophoblastic neoplasia: A report of 4 cases

BACKGROUND Gestational trophoblastic neoplasia (GTN) is a curable disease that involves the development of malignant tumor in the woman after a normal or molar pregnancy. The position of surgery in GTN is not properly specified and is changing due to new chemotherapy protocols. However, the role of surgery is highlighted in chemotherapy-resistant GTN. Other indications of surgery in trophoblast...

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fertility sparing surgery in gestational trophoblastic neoplasia: a report of 4 cases

background: gestational trophoblastic neoplasia (gtn) is a curable disease thatinvolves the development of malignant tumor in the woman after a normal or molarpregnancy. the position of surgery in gtn is not properly specified and is changingdue to new chemotherapy protocols. however, the role of surgery is highlighted inchemotherapy-resistant gtn. other indications of surgery in trophoblastic ...

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Gestational trophoblastic neoplasia.

Trophoblastic neoplasms are a truly fascinating set of diseases that arise from a failed gestation. A molar pregnancy is an allograft of fetal tissue typically containing only paternal chromosomes that may invade the maternal decidua following a failed gestation that may have arisen up to decades earlier. Choriocarcinoma (CCA), the most common malignant form of trophoblastic disease, represente...

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Outcome of subsequent pregnancy after treatment for persistent gestational trophoblastic tumour.

BACKGROUND This study analysed subsequent pregnancy outcome in patients treated for persistent gestational trophoblastic tumour (GTT). METHODS Between 1974 and 1999, a total of 378 patients with GTT (83 patients with high-risk and 295 patients with low-risk GTT) were treated at Chiba University Hospital, Japan. Of these 378 patients, 363 (96.0%) achieved primary remission and 315 survivors ha...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2001

ISSN: 1460-2350

DOI: 10.1093/humrep/16.2.360